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Gene Expression Data
Assay Details
Assay
Reference: J:248919 Yu W, et al., Irx1 regulates dental outer enamel epithelial and lung alveolar type II epithelial differentiation. Dev Biol. 2017 Sep 1;429(1):44-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258176
Gene symbol: Irx1
Gene name: Iroquois homeobox 1
Antibody: anti-Irx1 (HPA043160)
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Anti-Irx1 MGI:7258132 may have been used in this assay.
Results
Specimen 5A: postnatal adult (more )
Note: Triple labeled: green - Irx1; red - Sftpc (assay MGI:7258177); blue - DAPI.
Structure Level Pattern Image Note
TS28: lung alveolus Present Regionally restricted 5A Irx1 , 5A (merge)
Specimen 5A (inset): postnatal adult (more )
Note: Triple labeled: green - Irx1; red - Sftpc (assay MGI:7258177); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS28: lung alveolus type II pneumocyte Present 5A Irx1 (inset) , 5A (merge inset) Expression in some type II epithelial cells.
Specimen 8B: embryonic day 18.5 (more )
Note: Triple labeled: green - Irx1; red - Sox2 (assay MGI:7258179); blue - DAPI.
Structure Level Pattern Image Note
TS26: lower jaw incisor enamel organ Present Regionally restricted 8B Irx1 , 8B (merge) Expression in outer enamel epithelium cells, adjacent and separate from Sox2-expressing cells in labial cervical loop.
TS26: outer enamel epithelium Present Regionally restricted 8B Irx1 , 8B (merge) Expression in outer enamel epithelium cells, adjacent and separate from Sox2-expressing cells in labial cervical loop.
Specimen 8B (inset): embryonic day 18.5 (more )
Note: Triple labeled: green - Irx1; red - Sox2 (assay MGI:7258179); blue - DAPI.
Structure Level Pattern Image Note
TS26: lower jaw incisor enamel organ Present Regionally restricted 8B inset Expression in outer enamel epithelium cells, adjacent and separate from Sox2-expressing cells in labial cervical loop
TS26: outer enamel epithelium Present Regionally restricted 8B inset Expression in outer enamel epithelium cells, adjacent and separate from Sox2-expressing cells in labial cervical loop
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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