Bmp4 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:182768 Wong YL, et al., Smad1/Smad5 signaling in limb ectoderm functions redundantly and is required for interdigital programmed cell death. Dev Biol. 2012 Mar 1;363(1):247-57
Assay type:	RNA in situ
MGI Accession ID:	MGI:7257798
Gene symbol:	Bmp4
Gene name:	bone morphogenetic protein 4

Probe:

Bmp4 probe85

Results

5C ©

Specimen 5C: embryonic day 12.5; En1^tm2(cre)Wrst/En1⁺, Smad1^tm1Abr/Smad1⁺, Smad5^tm1Huy/Smad5^tm1Huy (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS20: forelimb interdigital region epithelium	Present		5C

5D ©

Specimen 5D: embryonic day 12.5; En1^tm2(cre)Wrst/En1⁺, Smad1^tm1Abr/Smad1^tm1Abr, Smad5^tm1Huy/Smad5^tm1Huy (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS20: forelimb interdigital region epithelium	Present	Regionally restricted	5D	Expression similar to controls. Ectopic expression in distal ectoderm.

S1A ©

Specimen S1A: embryonic day 11.5; En1^tm2(cre)Wrst/En1⁺, Smad1^tm1Abr/Smad1⁺, Smad5^tm1Huy/Smad5^tm1Huy (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS19: handplate apical ectodermal ridge	Present		S1A

S1B ©

Specimen S1B: embryonic day 11.5; En1^tm2(cre)Wrst/En1⁺, Smad1^tm1Abr/Smad1^tm1Abr, Smad5^tm1Huy/Smad5^tm1Huy (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS19: handplate apical ectodermal ridge	Strong		S1B	Elevated expression in apical ectodermal ridge.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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