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Gene Expression Data
Assay Details
Assay
Reference: J:180785 Loebel DA, et al., Regionalized Twist1 activity in the forelimb bud drives the morphogenesis of the proximal and preaxial skeleton. Dev Biol. 2012 Feb 15;362(2):132-40
Assay type: RNA in situ
MGI Accession ID: MGI:7256621
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe126
Probe preparation: labelled with digoxigenin RNA
Results
Specimen S5P: embryonic day 11.5; Twist1tm2Bhr/Twist1+ (more )
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present S5P
Specimen S5Q: embryonic day 11.5; Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present S5Q
Specimen S5R: embryonic day 11.5; Mesp1tm2(cre)Ysa/Mesp1+, Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present Regionally restricted S5R Domain of expression expanded anteriorly compared to wild type and heterozygous limb buds.
Specimen S5S: embryonic day 11.5; Twist1tm2Bhr/Twist1+ (more )
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present S5S
Specimen S5T: embryonic day 11.5; Mesp1tm2(cre)Ysa/Mesp1+, Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present Regionally restricted S5T Expression domain does not expand along dorsal-ventral axis, remaining within well-defined band in distal limb.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory