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Gene Expression Data
Assay Details
Assay
Reference: J:180785 Loebel DA, et al., Regionalized Twist1 activity in the forelimb bud drives the morphogenesis of the proximal and preaxial skeleton. Dev Biol. 2012 Feb 15;362(2):132-40
Assay type: RNA in situ
MGI Accession ID: MGI:7256611
Gene symbol: Msx1
Gene name: msh homeobox 1
Probe: Msx1 probe52
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 5J: embryonic day 10.5; Twist1tm2Bhr/Twist1+ (more )
Structure Level Pattern Image Note
TS17: limb mesenchyme Strong Regionally restricted 5J Strong expression in anterior mesenchyme.

Specimen 5K: embryonic day 10.5; Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Structure Level Pattern Image Note
TS17: limb mesenchyme Strong Regionally restricted 5K Strong expression in anterior mesenchyme.

Specimen 5L: embryonic day 10.5; Mesp1tm2(cre)Ysa/Mesp1+, Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted 5L Expression reduced compared to wild-type and heterozygote.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory