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Gene Expression Data
Assay Details
Assay
Reference: J:180785 Loebel DA, et al., Regionalized Twist1 activity in the forelimb bud drives the morphogenesis of the proximal and preaxial skeleton. Dev Biol. 2012 Feb 15;362(2):132-40
Assay type: RNA in situ
MGI Accession ID: MGI:7256610
Gene symbol: Grem1
Gene name: gremlin 1, DAN family BMP antagonist
Probe: Grem1 probe15
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 5G: embryonic day 10.5; Twist1tm2Bhr/Twist1+ (more )
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted 5G Expression in distal limb mesenchyme, with broader domain on posterior side of limb bud.
Specimen 5H: embryonic day 10.5; Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted 5H Slight anterior expansion of expression.
Specimen 5I: embryonic day 10.5; Mesp1tm2(cre)Ysa/Mesp1+, Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted 5I More pronounced anterior expansion of expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory