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Gene Expression Data
Assay Details
Assay
Reference: J:180785 Loebel DA, et al., Regionalized Twist1 activity in the forelimb bud drives the morphogenesis of the proximal and preaxial skeleton. Dev Biol. 2012 Feb 15;362(2):132-40
Assay type: RNA in situ
MGI Accession ID: MGI:7256605
Gene symbol: Alx4
Gene name: aristaless-like homeobox 4
Probe: Alx4 probe18
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 4D: embryonic day 10.5; Twist1tm2Bhr/Twist1+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 4D Expression in anterior one-third mesenchyme of forelimb bud.
Specimen 4E: embryonic day 10.5; Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 4E Expression not reduced compared with wild type.
Specimen 4F: embryonic day 10.5; Mesp1tm2(cre)Ysa/Mesp1+, Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 4F Reduced expression confined to anterior margin of forelimb bud.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory