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Gene Expression Data
Assay Details
Assay
Reference: J:199480 Cao T, et al., Mouse limbs expressing only the Gli3 repressor resemble those of Sonic hedgehog mutants. Dev Biol. 2013 Jul 15;379(2):221-8
Assay type: RNA in situ
MGI Accession ID: MGI:7256300
Gene symbol: Fgf4
Gene name: fibroblast growth factor 4
Probe: Fgf4 probe42
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4C1: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present Regionally restricted 4C1 Expresssion restricted to posterior 2/3rds of ectodermal ridge.
Specimen 4C2: embryonic day 10.5; Gli3tm3.1Blnw/Gli3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Weak Regionally restricted 4C2 Expression slightly weaker and more posteriorly restricted compared to wild type.
Specimen 4C3: embryonic day 10.5; Gli3tm3.1Blnw/Gli3tm3.1Blnw, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Absent 4C3
Specimen 4C4: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: forelimb bud Absent 4C4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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