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Gene Expression Data
Assay Details
Assay
Reference: J:321069 Lopez-Marquez A, et al., Sox9 is involved in the thyroid differentiation program and is regulated by crosstalk between TSH, TGFbeta and thyroid transcription factors. Sci Rep. 2022 Feb 9;12(1):2144
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6890428
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: Anti-Sox9 (AB5535)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 1A E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: thyroid primordium endoderm Weak Regionally restricted 1A E9.5 (merge) , 1A E9.5 Sox9 Weak expression in limited number of thyroid precursors.
TS15: pharynx mesenchyme Present Regionally restricted 1A E9.5 (merge) , 1A E9.5 Sox9 Higher levels of expression in mesenchyme adjacent to thyroid primordium.
Specimen 1A E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: thyroid primordium endoderm Present Regionally restricted 1A E10.5 (merge) , 1A E10.5 Sox9 Increased expression in thyroid primordium.
TS17: pharynx mesenchyme Strong Regionally restricted 1A E10.5 (merge) , 1A E10.5 Sox9 Higher levels of expression in mesenchyme adjacent to thyroid primordium.
Specimen 1A E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: thyroid gland Present Widespread 1A E11.5 (merge) , 1A E11.5 Sox9 Expression in all thyroid epithelial cells at E11.5.
TS19: pharynx mesenchyme Present Regionally restricted 1A E11.5 Sox9 , 1A E11.5 (merge) Expression in mesenchyme surrounding thyroid primordium maintained along different stages of embryonic development.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory