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Gene Expression Data
Assay Details
Assay
Reference: J:77401 Pennekamp P, et al., The ion channel polycystin-2 is required for left-right axis determination in mice. Curr Biol. 2002 Jun 4;12(11):938-43
Assay type: RNA in situ
MGI Accession ID: MGI:6885968
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Probe: Pitx2 cDNA9
Probe preparation: Antisense RNA
Results
Specimen 4A: embryonic day 8.5; Pkd2tm1Dwo/Pkd2+ (more )
Structure Level Pattern Image Note
TS13: head Present 4A
TS13: heart Present Regionally restricted 4A Expressed in the left side.
TS13: lateral plate mesoderm Present Regionally restricted 4A Expressed in the left side.

Specimen 4A': embryonic day 8.5; Pkd2tm1Dwo/Pkd2+ (more )
Structure Level Pattern Image Note
TS13: heart Present Regionally restricted 4A' Expressed in the left side.

Specimen 4A": embryonic day 8.5; Pkd2tm1Dwo/Pkd2+ (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present Regionally restricted 4A" Expressed in the left side.

Specimen 4A"': embryonic day 8.5; Pkd2tm1Dwo/Pkd2+ (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present Regionally restricted 4A'" Expressed in the left side.

Specimen 4B: embryonic day 8.5; Pkd2tm1Dwo/Pkd2tm1Dwo (more )
Structure Level Pattern Image Note
TS13: head Present 4B
TS13: lateral plate mesoderm Present 4B Bilaterally expressed, with a more posterior anterior limits compared to the heterozygous controls.
TS13: heart Absent 4B

Specimen 4B': embryonic day 8.5; Pkd2tm1Dwo/Pkd2tm1Dwo (more )
Structure Level Pattern Image Note
TS13: heart Absent 4B'

Specimen 4B": embryonic day 8.5; Pkd2tm1Dwo/Pkd2tm1Dwo (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present Regionally restricted 4B" Section to show the negative anterior region that supposed to be positive in the heterozygous controls.

Specimen 4B"': embryonic day 8.5; Pkd2tm1Dwo/Pkd2tm1Dwo (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present 4B'" Bilaterally expressed.

Specimen 4C: embryonic day 8.5; Pkd2tm1Dwo/Pkd2tm1Dwo (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present Regionally restricted 4C Bilaterally expressed, with a more posterior anterior limits compared to the heterozygous controls.
TS13: head Present 4C

Specimen 4D: embryonic day 8.5; Pkd2tm1Dwo/Pkd2tm1Dwo (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present Regionally restricted 4D Bilaterally expressed, with a more posterior anterior limits compared to the heterozygous controls.
TS13: head Present 4D inset , 4D

Specimen 4E: embryonic day 10.5-11.0; Pkd2tm1Dwo/Pkd2+ (more )
Structure Level Pattern Image Note
TS17: left lung Present 4E

Specimen 4F: embryonic day 10.5-11.0; Pkd2tm1Dwo/Pkd2tm1Dwo (more )
Structure Level Pattern Image Note
TS17: left lung Absent 4F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory