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Gene Expression Data
Assay Details
Assay
Reference: J:276249 Crerar H, et al., Regulation of NGF Signaling by an Axonal Untranslated mRNA. Neuron. 2019 May 8;102(3):553-563.e8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6885935
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH (#AB152)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 4D fl/fl (top): embryonic day 16.5; Trp53inp2tm1c(KOMP)Mbp/Trp53inp2tm1c(KOMP)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS24: heart sympathetic neuron Present 4D fl/fl (top)
Specimen 4D fl/fl (bottom): embryonic day 16.5; Trp53inp2tm1c(KOMP)Mbp/Trp53inp2tm1c(KOMP)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS24: heart sympathetic neuron Present 4D fl/fl (bottom)
Specimen 4D Th-Cre;fl/fl (top): embryonic day 16.5; Trp53inp2tm1c(KOMP)Mbp/Trp53inp2tm1c(KOMP)Mbp, Tg(Th-cre)#Gsat/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: heart sympathetic neuron Weak Regionally restricted 4D Th-Cre;fl/fl (top) Significant reduction in both density of innervation and axonal branching compared with control littermates.
Specimen 4D Th-Cre;fl/fl (bottom): embryonic day 16.5; Trp53inp2tm1c(KOMP)Mbp/Trp53inp2tm1c(KOMP)Mbp, Tg(Th-cre)#Gsat/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: heart sympathetic neuron Weak Regionally restricted 4D Th-Cre;fl/fl (bottom) Significant reduction in both density of innervation and axonal branching compared with control littermates.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory