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Gene Expression Data
Assay Details
Assay
Reference: J:276249 Crerar H, et al., Regulation of NGF Signaling by an Axonal Untranslated mRNA. Neuron. 2019 May 8;102(3):553-563.e8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6885932
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH (#AB152)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4C E16.5 fl/fl: embryonic day 16.5; Trp53inp2tm1c(KOMP)Mbp/Trp53inp2tm1c(KOMP)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS24: superior cervical ganglion sympathetic neuron Present 4C E16.5 fl/fl
Specimen 4C E16.5 Th-Cre;fl/fl: embryonic day 16.5; Trp53inp2tm1c(KOMP)Mbp/Trp53inp2tm1c(KOMP)Mbp, Tg(Th-cre)#Gsat/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: superior cervical ganglion sympathetic neuron Present 4C E16.5 Th-Cre;fl/fl Expression in normal numbers of sympathetic neurons at E16.5.
Specimen 4C P0.5 fl/fl: postnatal day 0.5; Trp53inp2tm1c(KOMP)Mbp/Trp53inp2tm1c(KOMP)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS27: superior cervical ganglion sympathetic neuron Present 4C P0.5 fl/fl
Specimen 4C P0.5 Th-Cre;fl/fl: postnatal day 0.5; Trp53inp2tm1c(KOMP)Mbp/Trp53inp2tm1c(KOMP)Mbp, Tg(Th-cre)#Gsat/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: superior cervical ganglion sympathetic neuron Present 4C P0.5 Th-Cre;fl/fl Authors report significant cell loss at birth (P0.5)
Specimen 4C P21 fl/fl: postnatal day 21; Trp53inp2tm1c(KOMP)Mbp/Trp53inp2tm1c(KOMP)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS28: superior cervical ganglion sympathetic neuron Present 4C P21 fl/fl
Specimen 4C P21 Th-Cre;fl/fl: postnatal day 21; Trp53inp2tm1c(KOMP)Mbp/Trp53inp2tm1c(KOMP)Mbp, Tg(Th-cre)#Gsat/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: superior cervical ganglion sympathetic neuron Present 4C P21 Th-Cre;fl/fl Authors report significant cell loss at 3 weeks after birth (P21).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory