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Gene Expression Data
Assay Details
Assay
Reference: J:49977 Yu BD, et al., MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10632-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6883718
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament clone 2H3
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: cranial ganglion Present 3A
Specimen 3B: embryonic day 10.0; Kmt2atm1Sjk/Kmt2atm1Sjk (more )
Structure Level Pattern Image Note
TS16: cranial ganglion Present 3B Morphology changes were noted in the mutant.
Specimen 3C: embryonic day 10.5; Kmt2atm1Sjk/Kmt2a+ (more )
Structure Level Pattern Image Note
TS17: cranial ganglion Present 3C
TS17: cranial nerve Present Regionally restricted 3C Prominent nerve tracts innervated the arches.
Specimen 3D: embryonic day 10.5; Kmt2atm1Sjk/Kmt2atm1Sjk (more )
Structure Level Pattern Image Note
TS16: cranial ganglion Present 3D Cranial ganglia continued to show unusual morphology and failed to elaborate nerve fibers toward branchial arches.
Specimen 3E: embryonic day 10.5; Kmt2atm1Sjk/Kmt2a+ (more )
Note: Flat mount. Double labeled: brown - Nefm; blue - Kmt2a reporter (assay MGI:6885588).
Structure Level Pattern Image Note
TS17: facial ganglion Present 3E
Specimen 3F: embryonic day 10.5; Kmt2atm1Sjk/Kmt2atm1Sjk (more )
Note: Flat mount. Double labeled: brown - Nefm; blue - Kmt2a reporter (assay MGI:6885588).
Structure Level Pattern Image Note
TS17: facial ganglion Present 3F
Specimen 4A: embryonic day 10.0 (more )
Note: Flat mount.
Structure Level Pattern Image Note
TS17: spinal ganglion Present 4A
TS17: spinal nerve Present 4A
Specimen 4B: embryonic day 10.0; Kmt2atm1Sjk/Kmt2atm1Sjk (more )
Note: Flat mount.
Structure Level Pattern Image Note
TS17: spinal ganglion Present 4B
TS17: spinal nerve Present 4B
Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: spinal ganglion Present 4C
Specimen 4D: embryonic day 10.5; Kmt2atm1Sjk/Kmt2atm1Sjk (more )
Structure Level Pattern Image Note
TS17: spinal ganglion Present 4D
Specimen 4E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: spinal ganglion Present 4E
Specimen 4F: embryonic day 10.5; Kmt2atm1Sjk/Kmt2atm1Sjk (more )
Structure Level Pattern Image Note
TS17: spinal ganglion Present 4F
Specimen 4G: embryonic day 10.5; Kmt2atm1Sjk/Kmt2a+ (more )
Structure Level Pattern Image Note
TS17: spinal ganglion Present 4G
TS17: spinal nerve Present 4G
Specimen 4H: embryonic day 10.5; Kmt2atm1Sjk/Kmt2atm1Sjk (more )
Structure Level Pattern Image Note
TS17: spinal ganglion Present 4H
TS17: spinal nerve Present 4H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory