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Gene Expression Data
Assay Details
Assay
Reference: J:316551 Kwon YR, et al., The Shh coreceptor Cdo is required for differentiation of midbrain dopaminergic neurons. Stem Cell Res. 2014 Sep;13(2):262-74
Assay type: RNA in situ
MGI Accession ID: MGI:6881733
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe201
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4D Cdo+/+ (upper): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Present Regionally restricted 4D Cdo+/+ (upper) Expression detected throughout ventral brain area.

Specimen 4D Cdo-/- (upper): embryonic day 9.5; Cdontm1Rsk/Cdontm1Rsk (more )
Structure Level Pattern Image Note
TS15: future brain Weak Regionally restricted 4D Cdo-/- (upper) Significant reduction of expression in ventral brain.

Specimen 4D Cdo+/+ (middle): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future midbrain Present 4D Cdo+/+ (middle)

Specimen 4D Cdo-/- (middle): embryonic day 9.5; Cdontm1Rsk/Cdontm1Rsk (more )
Structure Level Pattern Image Note
TS15: future midbrain Weak 4D Cdo-/- (middle) Significant reduction of expression in midbrain.

Specimen 4D Cdo+/+ (lower): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future midbrain Present 4D Cdo+/+ (lower)

Specimen 4D Cdo-/- (lower): embryonic day 9.5; Cdontm1Rsk/Cdontm1Rsk (more )
Structure Level Pattern Image Note
TS15: future midbrain Weak 4D Cdo-/- (lower) Significant reduction of expression in midbrain.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory