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Gene Expression Data
Assay Details
Assay
Reference: J:310000 Shapiro AM, et al., Breast cancer 1 (BRCA1)-deficient embryos develop normally but are more susceptible to ethanol-initiated DNA damage and embryopathies. Redox Biol. 2016 Apr;7:30-38
Assay type: Western blot
MGI Accession ID: MGI:6874602
Gene symbol: Brca1
Gene name: breast cancer 1, early onset
Antibody: anti-Brca1 (MAB22101)
Detection system: Secondary antibody
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex Note
WT E9.5 (a) TS15: embryo Present involves: 129S6/SvEvTac * C57BL/6J * CBA Not Specified wild-type littermate
def E9.5 (a) TS15: embryo Present (b) involves: 129S6/SvEvTac * C57BL/6J * CBA Brca1tm2Cxd/Brca1+, Edil3Tg(Sox2-cre)1Amc/0Not Specified Conditional mutant.
Notes:
(a) Age normalized so that noon of plug day = E0.5.
(b) Expression levels are reduced 28% in the heterozygote.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory