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Gene Expression Data
Assay Details
Assay
Reference: J:165134 Kim B, et al., Potential role for MATER in cytoplasmic lattice formation in murine oocytes. PLoS One. 2010;5(9):e12587
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6872314
Gene symbol: Padi6
Gene name: peptidyl arginine deiminase, type VI
Antibody: Anti-Padi6
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1A GV: postnatal week 4-6 (more )
Note: Germinal vesicle oocytes. Double labeled: red - Padi6; green - Nlrp5 (assay MGI:6872313).
Structure Level Pattern Image Note
TS28: primary oocyte Strong 1A GV Padi6 , 1A GV Merge Expression colocalized with Nlrp5 (Mater) strongly in the cortex and, to a lesser degree, in the cytoplasm of germinal vesicle stage oocytes.
Specimen 1A 2-cell: embryonic day 1.0 (more )
Note: Double labeled: red - Padi6; green - Nlrp5 (assay MGI:6872313).
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 1A 2-cell Merge , 1A 2-cell Padi6 Co-localization with Nlrp5 (Mater) was observed at the non-opposed cortex regions of 2-cell embryos with less co-localization being observed throughout the cytoplasm. Nlrp5 (Mater) staining penetrated deeper into the cytoplasm compared with Padi6.
Specimen 1A 4-cell: embryonic day 2.0 (more )
Note: Double labeled: red - Padi6; green - Nlrp5 (assay MGI:6872313).
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 1A 4-cell Merge , 1A 4-cell Padi6 Co-localization with Nlrp5 (Mater) was observed at the non-opposed cortex regions of 4-cell embryos with less co-localization being observed throughout the cytoplasm. Nlrp5 (Mater) staining penetrated deeper into the cytoplasm compared with Padi6.
Specimen 2A Mater+/+ Non-Extracted: postnatal week 4-6 (more )
Note: Germinal vesicle oocytes.
Structure Level Pattern Image Note
TS28: primary oocyte Present 2A Non-extracted Mater+/+
Specimen 2A Matertm/tm Non-Extracted: postnatal week 4-6; Nlrp5tm1Zbt/Nlrp5tm1Zbt (more )
Note: Germinal vesicle oocytes.
Structure Level Pattern Image Note
TS28: primary oocyte Present 2A Non-extracted Matertm/tm The level and localization of Padi6 was similar between Mater+/+ and Mater<tm/tm> oocytes with slightly reduced expression level at the cortex of the mutant oocytes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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