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Gene Expression Data
Assay Details
Assay
Reference: J:315518 Lee E, et al., Autophagy is essential for cardiac morphogenesis during vertebrate development. Autophagy. 2014 Apr;10(4):572-87
Assay type: RNA in situ
MGI Accession ID: MGI:6871038
Gene symbol: Tbx2
Gene name: T-box 2
Results
Specimen 6D Atg5+/+ (upper): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart Present Regionally restricted 6D Atg5+/+ (upper0 Expression normally restricted to myocardium of atrioventricular canal, inner curvature and outflow tract.
TS15: atrioventricular canal cardiac muscle Present 6D Atg5+/+ (upper0
TS15: outflow tract Present 6D Atg5+/+ (upper0
Specimen 6D Atg5+/+ (lower): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: atrioventricular canal Present 6D Atg5+/+ (lower)
Specimen Atg5+/- not shown: embryonic day 9.5; Atg5tm1Nmz/Atg5+ (more )
Structure Level Pattern Image Note
TS15: heart Present Regionally restricted Heterozygous littermates display normal expression.
Specimen 6D atg5/- (upper): embryonic day 9.5; Atg5tm1Nmz/Atg5tm1Nmz (more )
Structure Level Pattern Image Note
TS15: heart Present Regionally restricted 6D atg5/- (upper) Authors report mutants exhibit stronger or expanded, ectopic expression.
Specimen 6D atg5/- (lower): embryonic day 9.5; Atg5tm1Nmz/Atg5tm1Nmz (more )
Structure Level Pattern Image Note
TS15: atrioventricular canal Present Regionally restricted 6D atg5/- (lower) Expanded expression in atrioventricular canal.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory