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Gene Expression Data
Assay Details
Assay
Reference: J:243650 Herriges MJ, et al., The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis. Genes Dev. 2017 May 01;31(9):889-903
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6863969
Gene symbol: Hnf4a
Gene name: hepatic nuclear factor 4, alpha
Antibody: anti-Hnf4a (goat)
Detection system: Secondary antibody
Results
Specimen 6G: postnatal month 6; Nkx2-1tm1Ikono/Nkx2-1+, Sfta3-pstm1.1(cre/ERT2)Eem/Sfta3-ps+ (more )
Note: Double labeled: green - Hnf4a; red - Sox9 (assay MGI:6863968).
Structure Level Pattern Image Note
TS28: lung epithelium Present 6G Expression is seen in the distal bronchiolized epithelium. This expression is typically considered a marker of gastric stem cells.
Specimen S8E - 10 weeks: postnatal week 10; Nkx2-1tm1Ikono/Nkx2-1+, Sfta3-pstm1.1(cre/ERT2)Eem/Sfta3-ps+ (more )
Structure Level Pattern Image Note
TS28: lung alveolus Present S8E upper Ectopic expression is seen in the alveoli.
TS28: lobar bronchus Absent S8E upper As in wild type, no expression is seen in the airways.
Specimen S8E - 6 months: postnatal month 6; Nkx2-1tm1Ikono/Nkx2-1+, Sfta3-pstm1.1(cre/ERT2)Eem/Sfta3-ps+ (more )
Structure Level Pattern Image Note
TS28: lung alveolus Present S8E lower Ectopic expression is seen in the alveoli.
TS28: lobar bronchus Absent S8E lower As in wild type, no expression is seen in the airways.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory