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Gene Expression Data
Assay Details
Assay
Reference: J:243650 Herriges MJ, et al., The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis. Genes Dev. 2017 May 01;31(9):889-903
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6863941
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: anti-E-cadherin
Detection system: Secondary antibody
Results
Specimen 4C - Proximal - Wild-type: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: lung epithelium Present 4C Proximal Wild-type Expression is seen in the proximal airway.

Specimen 4C - Proximal - NANCIcreERT2-RFP/+; Nkx2.1GFP/+: postnatal day 4; Nkx2-1tm1Ikono/Nkx2-1+, Sfta3tm1.1(cre/ERT2)Eem/Sfta3+ (more )
Structure Level Pattern Image Note
TS28: lung epithelium Present 4C Proximal NANCIRFP/+; Nkx2.1GFP/+ In the proximal airway, defects in epithelial barrier integrity are observed.

Specimen 4C - Distal - Wild-type: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: lung epithelium Present 4C Distal Wild-type Expression is seen in the distal airway.

Specimen 4C - Distal - NANCIcreERT2-RFP/+; Nkx2.1GFP/+: postnatal day 4; Nkx2-1tm1Ikono/Nkx2-1+, Sfta3tm1.1(cre/ERT2)Eem/Sfta3+ (more )
Structure Level Pattern Image Note
TS28: lung Present 4C Distal NANCIRFP/+; Nkx2.1GFP/+ In the distal airway, defects in epithelial barrier integrity are observed, as well as expressing cells in the airway lumen.
TS28: lung epithelium Present 4C Distal NANCIRFP/+; Nkx2.1GFP/+ In the distal airway, defects in epithelial barrier integrity are observed, as well as expressing cells in the airway lumen.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory