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Gene Expression Data
Assay Details
Assay
Reference: J:158688 Seshadri S, et al., Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5622-7
Assay type: Western blot
MGI Accession ID: MGI:6861786
Gene symbol: Disc1
Gene name: disrupted in schizophrenia 1
Results
Image: 3C DISC1 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure 130 kDa 105 kDa 10 kDa Genetic BackgroundMutant Allele(s)Sex
BACE1-/- P0 TS27: cerebral cortex Present (a) Present (b) Present (b) involves: 129S1/Sv * 129X1/SvJ Bace1tm1Pcw/Bace1tm1PcwNot Specified
WT P0 TS27: cerebral cortex Present Present Present involves: 129S1/Sv * 129X1/SvJ Not Specified
Notes:
(a) There is a 44.1% reduction in expression in this mutant compared to wild-type littermates.
(b) Band strength in this mutant is the same as in wild-type.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory