About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:158688 Seshadri S, et al., Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5622-7
Assay type: Western blot
MGI Accession ID: MGI:6861786
Gene symbol: Disc1
Gene name: disrupted in schizophrenia 1
Results
Image: 3C DISC1 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure 130 kDa 105 kDa 10 kDa Genetic BackgroundMutant Allele(s)Sex
BACE1-/- P0 TS27: cerebral cortex Present (a) Present (b) Present (b) involves: 129S1/Sv * 129X1/SvJ Bace1tm1Pcw/Bace1tm1PcwNot Specified
WT P0 TS27: cerebral cortex Present Present Present involves: 129S1/Sv * 129X1/SvJ Not Specified
Notes:
(a) There is a 44.1% reduction in expression in this mutant compared to wild-type littermates.
(b) Band strength in this mutant is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory