About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:158688 Seshadri S, et al., Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5622-7
Assay type: Western blot
MGI Accession ID: MGI:6860638
Gene symbol: Disc1
Gene name: disrupted in schizophrenia 1
Results
Image: 3A DISC1 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure 130 kDa 105 kDa 100 kDa Genetic BackgroundMutant Allele(s)Sex
NRG1+/- P0 TS27: cerebral cortex Present (a) Present (b) Present (b) involves: 129P2/OlaHsd Nrg1tm1Cbm/Nrg1+Not Specified
WT P0 TS27: cerebral cortex Present Present Present involves: 129P2/OlaHsd Not Specified
Notes:
(a) There is a 23.6% decrease in expression compared to wild-type.
(b) Band strength in the heterozygote is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory