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Gene Expression Data
Assay Details
Assay
Reference: J:316998 Gu J, et al., Identification and characterization of the novel Col10a1 regulatory mechanism during chondrocyte hypertrophic differentiation. Cell Death Dis. 2014 Oct 16;5:e1469
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6852556
Gene symbol: mt-Co2
Gene name: mitochondrially encoded cytochrome c oxidase II
Antibody: Cox-2 antibody (sc-7951)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 6a (upper): embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: fibula Strong Regionally restricted 6a Cox-2 (upper) High level expression in nuclei of hypertrophic chondrocytes, but not in resting or proliferative chondrocytes.
Specimen 6a (lower): embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epiphyseal plate hypertrophic zone Strong Regionally restricted 6a Cox-2 (lower) High level expression in nuclei of hypertrophic chondrocytes, but not in resting or proliferative chondrocytes.
TS25: epiphyseal plate proliferative zone Absent 6a Cox-2 (lower)
TS25: epiphyseal plate resting zone Absent 6a Cox-2 (lower)
Specimen 6b Cox-2: postnatal week 4 (more )
Structure Level Pattern Image Note
TS28: tibia Strong Regionally restricted 6b Cox-2
TS28: epiphyseal plate hypertrophic zone Strong Regionally restricted 6b Cox-2 High level expression in nuclei of hypertrophic chondrocytes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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