About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:46856 Saucedo-Cardenas O, et al., Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):4013-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6842942
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH
Detection system: Secondary antibody coupled to biotin
Results
Specimen 2A: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: substantia nigra Present 2A

Specimen 2B: postnatal newborn; Nr4a2tm1Omc/Nr4a2tm1Omc (more )
Structure Level Pattern Image Note
TS27: substantia nigra Absent 2B

Specimen 3C: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: adrenal medulla Present 3C

Specimen 3D: postnatal newborn; Nr4a2tm1Omc/Nr4a2tm1Omc (more )
Structure Level Pattern Image Note
TS27: adrenal medulla Present 3D Expression in this mutant is the same as in wild-type.

Specimen 3E: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb glomerular layer Present Regionally restricted 3E Expression is in the periglomerular dopaminergic neurons.

Specimen 3F: postnatal newborn; Nr4a2tm1Omc/Nr4a2tm1Omc (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb glomerular layer Present 3F Expression in this mutant is the same as in wild-type.

Specimen 4D +/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain Present Regionally restricted 4D +/+ Expression is ventral.

Specimen 4D -/-: embryonic day 12.5; Nr4a2tm1Omc/Nr4a2tm1Omc (more )
Structure Level Pattern Image Note
TS20: midbrain Absent 4D -/-


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory