Lmnb2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:307035 Chen NY, et al., Increased expression of LAP2beta eliminates nuclear membrane ruptures in nuclear lamin-deficient neurons and fibroblasts. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2107770118
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6832807
Gene symbol:	Lmnb2
Gene name:	lamin B2

Antibody:

anti-Lamin B2

Results

Specimen S3A Lmnb1^fl/fl: embryonic day 18.5; Lmnb1^tm1.1Sgy/Lmnb1^tm1.1Sgy (more

)
Note: Double labeled: green - Lmnb2; red - Tmpo (assay MGI:6832801).

Structure	Level	Pattern	Image	Note
TS26: cerebral cortex	Present		S3A Lmnb1^fl/fl Lamin b2 , S3A Lmnb1^fl/fl merge

Specimen S3A Emx1-Cre;Lmnb1^fl/fl: embryonic day 18.5; Emx1^tm1(cre)Krj/Emx1⁺, Lmnb1^tm1.1Sgy/Lmnb1^tm1.1Sgy (more

)
Note: Conditional mutant. Double labeled: green - Lmnb2; red - Tmpo (assay MGI:6832801).

Structure	Level	Pattern	Image	Note
TS26: cerebral cortex	Present		S3A Emx1-Cre;Lmnb1^fl/fl Lamin B2 , S3A Emx1-Cre;Lmnb1^fl/fl merge	In this mutant distribution was disproportionately to one side of the nucleus compared to controls.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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