Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:307035 Chen NY, et al., Increased expression of LAP2beta eliminates nuclear membrane ruptures in nuclear lamin-deficient neurons and fibroblasts. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2107770118
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6832793
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-Cleaved Caspase-3
Assay notes:	The antibody used recognizes the cleaved form of the protein.

Results

Specimen 1E Lmnb1fl/fl;ROSAnT-nG: embryonic day 18.5; Gt(ROSA)26Sor^{tm1(CAG-tdTomato*,-EGFP*)Ees}/Gt(ROSA)26Sor^{tm1(CAG-tdTomato*,-EGFP*)Ees}, Lmnb1^tm1.1Sgy/Lmnb1^tm1.1Sgy (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebral cortex	Absent		1E Lmnb1fl/fl;ROSAnT-nG right , 1E Lmnb1fl/fl;ROSAnT-nG left

Specimen 1E Emx1-Cre;Lmnb1fl/fl;ROSAnT-nG: embryonic day 18.5; Emx1^tm1(cre)Krj/Emx1⁺, Gt(ROSA)26Sor^{tm1(CAG-tdTomato*,-EGFP*)Ees}/Gt(ROSA)26Sor^{tm1(CAG-tdTomato*,-EGFP*)Ees}, Lmnb1^tm1.1Sgy/Lmnb1^tm1.1Sgy (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: cortical plate	Present		1E Emx1-Cre;Lmnb1fl/fl;ROSAnT-nG right , 1E Emx1-Cre;Lmnb1fl/fl;ROSAnT-nG left
TS26: cerebral cortex ventricular zone	Absent		1E Emx1-Cre;Lmnb1fl/fl;ROSAnT-nG left , 1E Emx1-Cre;Lmnb1fl/fl;ROSAnT-nG right

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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