Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:306955 Moazzen H, et al., NOX2 Is Critical to Endocardial to Mesenchymal Transition and Heart Development. Oxid Med Cell Longev. 2020;2020:1679045
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6802132
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-activated Casp3
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

7a WT ©

Specimen 7a - WT: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: atrioventricular endocardial cushion	Present	Single cells	7a WT	Expression is seen in cells undergoing apoptosis.

7a Nox2-/- ©

Specimen 7a - Nox2-/-: embryonic day 10.5; Cybb^tm1Din/? (more

)
Note: This is an X linked gene; the sex of the analysed specimen was not reported.

Structure	Level	Pattern	Image	Note
TS17: atrioventricular endocardial cushion	Present	Single cells	7a Nox2-/-	Expression is seen in cells undergoing apoptosis; the number of these cells is two fold higher in the mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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