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Gene Expression Data
Assay Details
Assay
Reference: J:306246 He M, et al., Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 2020 Apr 14;9:e53085
Assay type: RNA in situ
MGI Accession ID: MGI:6781983
Gene symbol: Sostdc1
Gene name: sclerostin domain containing 1
Probe: Mm-Sostdc1 (313151)
Probe preparation: Antisense
Visualized with: Fluorescence
Assay notes: RNAscope assay.
Results
Specimen 7D wt: embryonic day 16.0 (more )
Note: Triple labeled: magenta - Sostdc1; teal - Foxj1 (assay MGI:6781966); yellow - Ccl20 (assay MGI:6781984).
Structure Level Pattern Image Note
TS24: trachea epithelium Present Regionally restricted 7D wt Sostdc1 , 7D wt merge Expression is seen in cells in a basal state, likely progenitors.
Specimen 7D Ano1-/-: embryonic day 16.0; Ano1tm1Bdh/Ano1tm1Bdh (more )
Note: Triple labeled: magenta - Sostdc1; teal - Foxj1 (assay MGI:6781966); yellow - Ccl20 (assay MGI:6781984).
Structure Level Pattern Image Note
TS24: trachea epithelium Weak Regionally restricted 7D Ano1-/- Sostdc1 , 7D Ano1-/- merge Expression is significantly downregulated in the mutant; there are fewer basal state cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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