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Gene Expression Data
Assay Details
Assay
Reference: J:121242 Khandekar M, et al., A Gata2 intronic enhancer confers its pan-endothelia-specific regulation. Development. 2007 May;134(9):1703-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6781837
Gene symbol: Flt4
Gene name: FMS-like tyrosine kinase 4
Antibody: anti-VEGFR3
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 1M: embryonic day 11.5; Gata2tm1Mym/Gata2+ (more )
Structure Level Pattern Image Note
TS19: cardinal vein Weak 1M
TS19: dorsal aorta Weak 1M
TS19: lymphatic system Present Regionally restricted 1M Expressed in scattered cells lying near the cardinal vein.
Specimen 1O: embryonic day 11.5; Gata2tm1Mym/Gata2+ (more )
Note: Double labeled: red - Flt4; green - Prox1 (assay MGI:6781839).
Structure Level Pattern Image Note
TS19: lymphatic system Present Regionally restricted 1O Expressed in clustered cells in the vicinity of the anterior cardinal vein. Positive cells displayed anti-Prox1 nuclear staining.
TS19: cardinal vein Weak 1O
TS19: dorsal aorta Weak 1O
Specimen 1P/R: postnatal day 1; Gata2tm1Mym/Gata2+ (more )
Note: Double labeled: red - Flt4; green - Gata2 (assay MGI:6781836).
Structure Level Pattern Image Note
TS27: lymphatic vessel endothelium Present 1R , 1P
TS27: blood vessel endothelium Absent 1R , 1P
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory