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Gene Expression Data
Assay Details
Assay
Reference: J:310332 Lee MJ, et al., Sox2 contributes to tooth development via Wnt signaling. Cell Tissue Res. 2016 Jul;365(1):77-84
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6771646
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1a: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Present 1a
TS20: dental placode Present Widespread 1a Expression in most regions of dental epithelium.
Specimen 1b: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tooth epithelium Present Regionally restricted 1b Expression highly localized to lingual side of dental epithelium.
Specimen 1c: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tooth epithelium Present Regionally restricted 1c Strong expression on lingual side of dental epithelium; weak expression on buccal side of dental epithelium.
Specimen 1d: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: outer enamel epithelium Strong Regionally restricted 1d Strong expression on lingual side of outer enamel epithelium.
TS23: dental lamina Present 1d
TS23: oral epithelium Present 1d
Specimen 1e: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: tooth epithelium Present 1e
TS26: dental lamina Present Regionally restricted 1e Expression in dental lamina connecting molar1, molar 2 and molar-3-forming regions.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory