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Gene Expression Data
Assay Details
Assay
Reference: J:272572 May AJ, et al., Diverse progenitor cells preserve salivary gland ductal architecture after radiation-induced damage. Development. 2018 Nov 5;145(21):dev166363
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6758240
Gene symbol: Krt5
Gene name: keratin 5
Antibody: Anti-Keratin 5 (PRB-160P)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S1A upper: postnatal adult (more )
Note: Triple labeled: green - Krt5; blue - Cdh1 (assay MGI:6758242); red - Krt14 (assay MGI:6757233).
Structure Level Pattern Image Note
TS28: submandibular duct Present S1A upper left , S1A upper middle Colocalizes with Krt14 in ductal progenitors.
Specimen S1A lower: postnatal adult (more )
Note: Triple labeled: green - Krt5; blue - Cdh1 (assay MGI:6758242); red - Acta2 (assay MGI:6757239).
Structure Level Pattern Image Note
TS28: submandibular duct Present Regionally restricted S1A lower right , S1A lower left Colocalizes with Krt14 in Acta2- ductal progenitors.
Specimen S1D P2: postnatal day 2 (more )
Note: Double labeled: green - Krt5; red - Krt14 (assay MGI:6757233).
Structure Level Pattern Image Note
TS27: submandibular duct Weak S1D P2 middle , S1D P2 left Expressed by a subset of Krt14+ basal ductal cells, not expressed by myoepithelial cells.
Specimen S1D P7: postnatal day 7 (more )
Note: Double labeled: green - Krt5; red - Krt14 (assay MGI:6757233).
Structure Level Pattern Image Note
TS28: submandibular duct Weak S1D P7 left , S1D P7 middle Expressed by a subset of Krt14+ basal ductal cells, not expressed by myoepithelial cells.
Specimen S1D P14: postnatal day 14 (more )
Note: Double labeled: green - Krt5; red - Krt14 (assay MGI:6757233).
Structure Level Pattern Image Note
TS28: submandibular duct Present S1D P14 left , S1D P14 middle Expressed by a subset of Krt14+ basal ductal cells.
Specimen S1D P30: postnatal day 30 (more )
Note: Double labeled: green - Krt5; red - Krt14 (assay MGI:6757233).
Structure Level Pattern Image Note
TS28: submandibular duct Present S1D P30 middle , S1D P30 left Expressed by a subset of Krt14+ basal ductal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory