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Gene Expression Data
Assay Details
Assay
Reference: J:272572 May AJ, et al., Diverse progenitor cells preserve salivary gland ductal architecture after radiation-induced damage. Development. 2018 Nov 5;145(21):dev166363
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6758238
Gene symbol: Kit
Gene name: KIT proto-oncogene receptor tyrosine kinase
Antibody: anti-c-Kit (M-14; sc-1494)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1B: postnatal week 6 (more )
Note: Double labeled: green - Kit; red - Cdh1 (assay MGI:6758239).
Structure Level Pattern Image Note
TS28: submandibular duct Present 1B Expressed in intercalated ducts and granulated ducts, although at a substantially lower level in the latter.
Specimen 2D P2: postnatal day 2 (more )
Note: Double labeled: green - Kit; red - EdU.
Structure Level Pattern Image Note
TS27: submandibular duct Present 2D P2 No longer expressed by acinar cells and became localized to early luminal and basal ductal cells.
Specimen 2D P7: postnatal day 7 (more )
Note: Double labeled: green - Kit; red - EdU.
Structure Level Pattern Image Note
TS28: submandibular duct Present 2D P7 Expressed throughout the developing granulated ducts, albeit at lower levels compared with that in the intercalated duct cells.
Specimen 2D P14: postnatal day 14 (more )
Note: Double labeled: green - Kit; red - EdU.
Structure Level Pattern Image Note
TS28: submandibular duct Present 2D P14 Positve ductal cells increased significantly from P7 to P14. Expressed throughout the developing granulated ducts, albeit at lower levels compared with that in the intercalated duct cells. Reduced proliferation rate.
Specimen 2D P30: postnatal day 30 (more )
Note: Double labeled: green - Kit; red - EdU.
Structure Level Pattern Image Note
TS28: submandibular duct Present 2D P30 Expressed in the majority of intercalated duct and granulated duct cells. Reduced proliferation rate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory