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Gene Expression Data
Assay Details
Assay
Reference: J:249183 Saxon JG, et al., BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling. Dev Biol. 2017 Oct 1;430(1):113-128
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6726492
Gene symbol: Postn
Gene name: periostin, osteoblast specific factor
Antibody: anti-periostin
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 9G: embryonic day 13.5; Bmp2tm1.1Mis/Bmp2+ (more )
Structure Level Pattern Image Note
TS21: atrioventricular endocardial cushion Present 9G
Specimen 9H: embryonic day 13.5; Bmp2tm1.1Mis/Bmp2tm1Brd, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: atrioventricular endocardial cushion Present 9H Reduced expression compared with the control.
Specimen 13E: postnatal day 5; Bmp2tm1.1Mis/Bmp2+ (more )
Structure Level Pattern Image Note
TS28: mitral valve Present Regionally restricted 13E Expressed in the fibrosa.
Specimen 13F: postnatal day 5; Bmp2tm1.1Mis/Bmp2tm1Brd, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: mitral valve Present 13F Entirely dispersed in the enlarged mutant mitral valve leaflets.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory