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Gene Expression Data
Assay Details
Assay
Reference: J:228503 Altieri SC, et al., En1 directs superior olivary complex neuron positioning, survival, and expression of FoxP1. Dev Biol. 2015 Dec 1;408(1):99-108
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6725825
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 7C'/C": embryonic day 14.5; En1tm2(cre)Wrst/En1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: green - Sox2; red - Cre reporter.
Structure Level Pattern Image Note
TS22: brainstem nucleus Present Regionally restricted 7C'/C" Co-expressed with En1-cre in the presumptive medial nucleus in the superior olivary nucleus.
Specimen 7D'/D": embryonic day 14.5; En1tm2(cre)Wrst/En1tm2(cre)Wrst, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: green - Sox2; red - Cre reporter.
Structure Level Pattern Image Note
TS22: brainstem nucleus Present Regionally restricted 7D'/D" Co-expressed with En1-cre in the presumptive medial nucleus in the superior olivary nucleus, similar as in the contral.
Specimen S2C'/C": postnatal day 0; En1tm2(cre)Wrst/En1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: green - Sox2; red - Cre reporter.
Structure Level Pattern Image Note
TS27: superior olivary nucleus Present Widespread S2C'/C" Co-expressed with En1-cre throughout the superior olivary nucleus.
Specimen S2D'/D": postnatal day 0; En1tm2(cre)Wrst/En1tm2(cre)Wrst, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: green - Sox2; red - Cre reporter.
Structure Level Pattern Image Note
TS27: superior olivary nucleus Present Regionally restricted S2D'/D" Cells co-expressed with En1-cre only in ectopic cell group.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
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