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Gene Expression Data
Assay Details
Assay
Reference: J:222440 Huang J, et al., Bmp4 from the optic vesicle specifies murine retina formation. Dev Biol. 2015 Jun 1;402(1):119-26
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6725152
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to fluorescein
Results
Specimen 2A: embryonic day 10.5; Bmp4tm4Blh/Bmp4tm4Blh (more )
Structure Level Pattern Image Note
TS17: lens pit Present 2A
TS17: retina Present 2A

Specimen 2B: embryonic day 10.5; Bmp4tm4Blh/Bmp4tm4Blh, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: eye surface ectoderm Absent 2B prospective lens
TS17: retina Trace 2B Greatly reduced expression in the prospective retina.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory