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Gene Expression Data
Assay Details
Assay
Reference: J:160668 Yang H, et al., Gfi1-Cre knock-in mouse line: A tool for inner ear hair cell-specific gene deletion. Genesis. 2010 Apr 13;48(6):400-406
Assay type: RNA in situ
MGI Accession ID: MGI:6725122
Gene symbol: Gfi1
Gene name: growth factor independent 1 transcription repressor
Probe: Gfi1 cDNA4
Probe preparation: Antisense RNA
Results
Specimen 2a: embryonic day 13.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: lateral semicircular canal epithelium Present Regionally restricted 2a Expression is seen in hair cells.
Specimen not shown - E13.5: embryonic day 13.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: posterior semicircular canal epithelium Present Regionally restricted Expression is seen in hair cells.
TS21: superior semicircular canal epithelium Present Regionally restricted Expression is seen in hair cells.
TS21: vestibulo-cochlear ganglion Absent
Specimen 2b: embryonic day 13.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: utricle epithelium Present Regionally restricted 2b Expression is seen in hair cells.
Specimen 2c: embryonic day 13.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: saccule epithelium Present Regionally restricted 2c Expression is seen in hair cells.
Specimen 2d: embryonic day 14.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: lateral semicircular canal epithelium Present Regionally restricted 2d Expression is seen in hair cells.
TS22: macula of utricle Present Regionally restricted 2d Expression is seen in hair cells.
Specimen not shown - E14.5: embryonic day 14.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: posterior semicircular canal epithelium Present Regionally restricted Expression is seen in hair cells.
TS22: superior semicircular canal epithelium Present Regionally restricted Expression is seen in hair cells.
TS22: vestibulo-cochlear ganglion Absent
Specimen 2e: embryonic day 14.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: saccule epithelium Present Regionally restricted 2e Expression is seen in hair cells.
Specimen 2f: embryonic day 15.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: lateral semicircular canal epithelium Present Regionally restricted 2f Expression is seen in hair cells.
TS23: macula of utricle Present Regionally restricted 2f Expression is seen in hair cells.
Specimen not shown - E15.5: embryonic day 15.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: posterior semicircular canal epithelium Present Regionally restricted Expression is seen in hair cells.
TS23: superior semicircular canal epithelium Present Regionally restricted Expression is seen in hair cells.
TS23: vestibulo-cochlear ganglion Absent
Specimen 2g: embryonic day 15.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: saccule epithelium Present Regionally restricted 2g Expression is seen in hair cells.
Specimen 2h: embryonic day 16.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: lateral semicircular canal epithelium Present Regionally restricted 2h Expression is seen in hair cells.
TS24: macula of utricle Present Regionally restricted 2h Expression is seen in hair cells.
Specimen not shown - E16.5: embryonic day 16.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: posterior semicircular canal epithelium Present Regionally restricted Expression is seen in hair cells.
TS24: superior semicircular canal epithelium Present Regionally restricted Expression is seen in hair cells.
TS24: vestibulo-cochlear ganglion Absent
Specimen 2i: embryonic day 16.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: saccule epithelium Present Regionally restricted 2i Expression is seen in hair cells.
Specimen 2j: embryonic day 17.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: saccule epithelium Present Regionally restricted 2j Expression is seen in hair cells.
Specimen 2k: embryonic day 17.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: lateral semicircular canal epithelium Present Regionally restricted 2k Expression is seen in hair cells.
Specimen not shown - E17.5: embryonic day 17.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: macula of utricle Present Regionally restricted Expression is seen in hair cells.
TS25: posterior semicircular canal epithelium Present Regionally restricted Expression is seen in hair cells.
TS25: superior semicircular canal epithelium Present Regionally restricted Expression is seen in hair cells.
TS25: vestibulo-cochlear ganglion Absent
Specimen 2l: postnatal day 0; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: saccule epithelium Present Regionally restricted 2l Expression is seen in hair cells.
Specimen not shown - P0: postnatal day 0; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: osseus semicircular canal Present Regionally restricted Expression is seen in hair cells.
TS27: vestibulo-cochlear ganglion Absent
Specimen 3a: embryonic day 13.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: cochlea Absent 3a No hair cells are detected in the basal (or middle or apical) cochlea at this age.
Specimen 3b: embryonic day 14.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: cochlea Absent 3b No hair cells are detected in the basal (or middle or apical) cochlea at this age.
Specimen 3c: embryonic day 15.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cochlea epithelium Present Regionally restricted 3c Expression is seen in the inner and outer hair cells of the basal cochlea; it is not seen in the middle and apical cochlea.
Specimen 3d: embryonic day 16.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: cochlea epithelium Present Regionally restricted 3d Expression is seen in the inner and outer hair cells of the basal and middle cochlea; it is not seen in the apical cochlea.
Specimen 3e: embryonic day 17.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: cochlea epithelium Present Regionally restricted 3e Expression is seen in the inner and outer hair cells throughout the cochlea (basal, middle and apical).
Specimen not shown - E18.5: embryonic day 18.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cochlea epithelium Present Regionally restricted Expression is seen in the inner and outer hair cells throughout the cochlea (basal, middle and apical).
TS26: vestibulo-cochlear ganglion Absent
Specimen 3f: postnatal day 0; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cochlea epithelium Present Regionally restricted 3f Expression is seen in the inner and outer hair cells.
TS27: cochlear ganglion Absent 3f The apparent expression in the spiral ganglion is due to background signal.
Specimen not shown - P4: postnatal day 4; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cochlea epithelium Present Regionally restricted Expression is seen in the inner and outer hair cells throughout the cochlea (basal, middle and apical).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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