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Gene Expression Data
Assay Details
Assay
Reference: J:287761 Pineault KM, et al., Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life. Nat Commun. 2019 Jul 18;10(1):3168
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6724558
Gene symbol: Sp7
Gene name: Sp7 transcription factor 7
Antibody: Anti-Sp7/Osterix antibody (ab22552)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 1b: embryonic day 14.5; Hoxa11tm1Dmwe/Hoxa11+ (more )
Note: Double labeled: magenta - Sp7; green - Hoxa11 reporter (assay MGI:6724551).
Structure Level Pattern Image Note
TS22: radius cartilage condensation Present Regionally restricted 1b inset Expression is seen in preosteoblasts.
TS22: ulna cartilage condensation Present Regionally restricted 1b inset Expression is seen in preosteoblasts.
Specimen 1g: postnatal week 8; Hoxa11tm1Dmwe/Hoxa11+ (more )
Note: Double labeled: red - Sp7; green - Hoxa11 reporter (assay MGI:6724551).
Structure Level Pattern Image Note
TS28: long bone Present Regionally restricted 1g red , 1g merge Expression is seen in osteoprogenitors.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory