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Gene Expression Data
Assay Details
Assay
Reference: J:96968 Sagai T, et al., Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb. Development. 2005 Feb;132(4):797-803
Assay type: RNA in situ
MGI Accession ID: MGI:6719068
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe197
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 6A Expression is in the posterior mesenchyme.
TS17: hindlimb bud mesenchyme Present Regionally restricted 6A Expression is in the posterior mesenchyme.

Specimen 6B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 6B Expression is in the posterior mesenchyme.

Specimen 6C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Present Regionally restricted 6C Expression is in the posterior mesenchyme.

Specimen 6D: embryonic day 10.5; Rr29tm1.1Tshir/Rr29+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 6D Expression is in the posterior mesenchyme.
TS17: hindlimb bud mesenchyme Present Regionally restricted 6D Expression is in the posterior mesenchyme.

Specimen 6E: embryonic day 10.5; Rr29tm1.1Tshir/Rr29+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 6E Expression is in the posterior mesenchyme.

Specimen 6F: embryonic day 10.5; Rr29tm1.1Tshir/Rr29+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Present Regionally restricted 6F Expression is in the posterior mesenchyme.

Specimen 6G: embryonic day 10.5; Rr29tm1.1Tshir/Rr29tm1.1Tshir (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Absent 6G
TS17: hindlimb bud mesenchyme Absent 6G

Specimen 6H: embryonic day 10.5; Rr29tm1.1Tshir/Rr29tm1.1Tshir (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Absent 6H

Specimen 6I: embryonic day 10.5; Rr29tm1.1Tshir/Rr29tm1.1Tshir (more )
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Absent 6I

Specimen not shown: embryonic day 10.5; Rr29tm1.1Tshir/Rr29tm1.1Tshir (more )
Structure Level Pattern Image Note
TS17: neural tube Present Expression in these tissus is the same as in wild-type.
TS17: notochord Present Expression in these tissus is the same as in wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory