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Gene Expression Data
Assay Details
Assay
Reference: J:181189 Ishimura A, et al., Jmjd5, an H3K36me2 histone demethylase, modulates embryonic cell proliferation through the regulation of Cdkn1a expression. Development. 2012 Feb;139(4):749-59
Assay type: RNA in situ
MGI Accession ID: MGI:6719053
Gene symbol: Cdkn1a
Gene name: cyclin dependent kinase inhibitor 1A
Probe: Cdkn1a cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4E +/+: embryonic day 8.25 (more )
Structure Level Pattern Image Note
TS13: primitive streak Strong 4E +/+
TS13: embryo Present Regionally restricted 4E +/+ Expression is in the posterior half.
Specimen 4E delta/delta: embryonic day 8.25; Kdm8tm1.2Tasu/Kdm8tm1.2Tasu (more )
Structure Level Pattern Image Note
TS13: primitive streak Present 4E delta/delta
TS13: embryo Present 4E delta/delta Expression is in the posterior and there is ectopic expression in the anterior half (7 out of 10 embryos).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory