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Gene Expression Data
Assay Details
Assay
Reference: J:290862 Fulmer D, et al., Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin. Dev Biol. 2020 Jul 1;463(1):26-38
Assay type: Western blot
MGI Accession ID: MGI:6718532
Gene symbol: Gli3
Gene name: GLI-Kruppel family member GLI3
Antibody: anti-Gli3
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Image: S7A ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Size Not Specified (b) Genetic BackgroundMutant Allele(s)Sex Note
cHET P0 TS27: mitral valve Present Present involves: 129S1/Sv * 129X1/SvJ * C57BL/6J Dzip1tm1Sasl/Dzip1+, Nfatc1tm1.1(cre)Bz/Nfatc1+Not Specified Conditional mutant. anterior leaflet
WT P0 TS27: mitral valve Present Present Not Specified Not Specified anterior leaflet
cKO P0 TS27: mitral valve Present Present involves: 129S1/Sv * 129X1/SvJ * C57BL/6J Dzip1tm1Sasl/Dzip1tm1Sasl, Nfatc1tm1.1(cre)Bz/Nfatc1+Not Specified Conditional mutant. anterior leaflet
Notes:
(a) Gli3FL: full length transcriptional activator. No statistically significant change in the ratio's between Gli3FL/Gli3R among the wild-type, heterozygous and homozygous.
(b) Gli3R: GLI3 repressor
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory