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Gene Expression Data
Assay Details
Assay
Reference: J:278880 Li Y, et al., Embryonic senescent cells re-enter cell cycle and contribute to tissues after birth. Cell Res. 2018 Jul;28(7):775-778
Assay type: Recombinase reporter
MGI Accession ID: MGI:6716933
Gene symbol: Cdkn1a
Gene name: cyclin dependent kinase inhibitor 1A
Reporter: tdTomato
Direct Detection
Assay notes: mice were treated with tamoxifen at E10.5
Results
Specimen Fig1 E12.5: embryonic day 12.5; Cdkn1aem3(cre/ERT)Smoc/Cdkn1a+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: limb interdigital region Present 1j E12.5 in senescent cells in the apical ectodermal ridge (AER) and interdigital region of developing forelimbs at mid-embryonic stage
Specimen Fig1 E13.5: embryonic day 13.5; Cdkn1aem3(cre/ERT)Smoc/Cdkn1a+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: limb interdigital region Present 1j E13.5 in senescent cells in the apical ectodermal ridge (AER) and interdigital region of developing forelimbs at mid-embryonic stage
Specimen Fig1 E14.5: embryonic day 14.5; Cdkn1aem3(cre/ERT)Smoc/Cdkn1a+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: limb interdigital region Present 1j E14.5 in senescent cells in the apical ectodermal ridge (AER) and interdigital region of developing forelimbs at mid-embryonic stage
Specimen Fig1 E15.5: embryonic day 15.5; Cdkn1aem3(cre/ERT)Smoc/Cdkn1a+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: limb interdigital region Present 1j E15.5 in senescent cells in the apical ectodermal ridge (AER) and interdigital region of developing forelimbs at mid-embryonic stage
Specimen Fig1 E16.5: embryonic day 16.5; Cdkn1aem3(cre/ERT)Smoc/Cdkn1a+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: limb interdigital region Present 1j E16.5 in senescent cells in the apical ectodermal ridge (AER) and interdigital region of developing forelimbs at mid-embryonic stage
Specimen Fig1 P0: postnatal day 0; Cdkn1aem3(cre/ERT)Smoc/Cdkn1a+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: limb interdigital region Present 1j P0 in senescent cells in the apical ectodermal ridge (AER) and interdigital region of developing forelimbs at mid-embryonic stage
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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