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Gene Expression Data
Assay Details
Assay
Reference: J:160668 Yang H, et al., Gfi1-Cre knock-in mouse line: A tool for inner ear hair cell-specific gene deletion. Genesis. 2010 Apr 13;48(6):400-406
Assay type: Recombinase reporter
MGI Accession ID: MGI:6716842
Gene symbol: Gfi1
Gene name: growth factor independent 1 transcription repressor
Reporter: lacZ
Antibody: anti-B-galactosidase (ab9361)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen Fig4: postnatal day 0; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cochlea Present 4a present in outter hair cells and inner hair cells
TS27: saccule Present 4b percentages of hair cells expressing lacZ were 90.53%
TS27: utricle Present 4c percentages of hair cells expressing lacZ were 90.50%
TS27: crista ampullaris Present 4d percentages of hair cells expressing lacZ were 87.93%

Specimen Fig4 WM: postnatal day 0; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cochlea Present 4e percentages of hair cells expressing lacZ were 93.00% +/- 5.35%

Specimen Fig5 E16.5: embryonic day 16.5; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: retina layer Present 5m in ganglion cell layer

Specimen Fig5 P14: postnatal day 14; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present 5o


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/04/2024
MGI 6.13
The Jackson Laboratory