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Gene Expression Data
Assay Details
Assay
Reference: J:221163 Lim J, et al., BMP-Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse. Dev Biol. 2015 Apr 1;400(1):132-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6715569
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: anti-Sox9
Detection system: Alexa Fluor 488
Results
Specimen 5B Sox9 WT: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 5B Sox9 WT

Specimen 5B Sox9 PS4: embryonic day 11.5; Smad4tm2.1Cxd/Smad4tm2.1Cxd, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Present 5B Sox9 PS4 Authors report expression in the normal domain.

Specimen 5C WT: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb Present Regionally restricted 5C WT

Specimen 5C PS4: embryonic day 13.5; Smad4tm2.1Cxd/Smad4tm2.1Cxd, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: forelimb Weak Regionally restricted 5C PS4 Expression notably reduced.
TS21: forelimb digit Absent 5C PS4 Expression absent in presumptive digit arrays.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory