About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:221163 Lim J, et al., BMP-Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse. Dev Biol. 2015 Apr 1;400(1):132-8
Assay type: RNA in situ
MGI Accession ID: MGI:6715567
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Results
Specimen 5A E10.5 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 5A E10.5 WT
Specimen 5A E10.5 PS4: embryonic day 10.5; Smad4tm2.1Cxd/Smad4tm2.1Cxd, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Present 5A E10.5 PS4 Authors report expression was relatively normal in mutant at E10.5
Specimen 5A E12.0 WT: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: forearm Present 5A E12.0 WT Expression normally demarcates autopod and zeugopod elements.
TS20: hand Present 5A E12.0 WT Expression normally demarcates autopod and zeugopod elements.
TS20: upper arm mesenchyme Present Regionally restricted 5A E12.0 WT Expression in proximal mesenchyme.
Specimen 5A E12.0 PS4: embryonic day 12.0; Smad4tm2.1Cxd/Smad4tm2.1Cxd, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: forearm Ambiguous 5A E12.0 PS4 Expression largely undetectable in autopod and zeugopod regions.
TS20: hand Ambiguous 5A E12.0 PS4 Expression largely undetectable in autopod and zeugopod regions.
TS20: upper arm mesenchyme Weak Regionally restricted 5A E12.0 PS4 Lower level of expression in proximal mesenchyme
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory