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Gene Expression Data
Assay Details
Assay
Reference: J:263030 Hu J, et al., WDR1-regulated actin dynamics is required for outflow tract and right ventricle development. Dev Biol. 2018 Jun 15;438(2):124-137
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6715553
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Results
Specimen 6A: embryonic day 9.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1+ (more )
Note: Conditional mutant. Triple labeled: gray - Ctnnb1; green - Tnnt2 (assay MGI:6715546); red - phalloidin.
Structure Level Pattern Image Note
TS15: outflow tract Present Regionally restricted 6A Authors report proximal outflow tract composed of compact and tidily aligned monolayed/bilayed cardiomyocytes.
Specimen 6B: embryonic day 9.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1tm1.1Zzy (more )
Note: Conditional mutant. Triple labeled: gray - Ctnnb1; green - Tnnt2 (assay MGI:6715546); red - phalloidin.
Structure Level Pattern Image Note
TS15: outflow tract Present Regionally restricted 6B Organization of cardiac layers disrupted: cardiomyocytes loosely and disorderly arranged, and myocardium multilayered.
Specimen 6C: embryonic day 9.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1+ (more )
Note: Conditional mutant. Double labeled: gray - Ctnnb1; green and red - Cre reporter.
Structure Level Pattern Image Note
TS15: outflow tract Present Regionally restricted 6C Authors report proximal outflow tract composed of compact and tidily aligned monolayed/bilayed cardiomyocytes.
Specimen 6D: embryonic day 9.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1tm1.1Zzy (more )
Note: Conditional mutant. Double labeled: gray - Ctnnb1; green and red - Cre reporter.
Structure Level Pattern Image Note
TS15: outflow tract Present Regionally restricted 6D Organization of cardiac layers disrupted: cardiomyocytes loosely and disorderly arranged, and myocardium multilayered.
Specimen 6E/G: embryonic day 9.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1+ (more )
Note: Conditional mutant. Double labeled: gray - Ctnnb1; green and red - Cre reporter.
Structure Level Pattern Image Note
TS15: outflow tract Present Regionally restricted 6G , 6E Authors report proximal outflow tract composed of compact and tidily aligned monolayed/bilayed cardiomyocytes.
Specimen 6F/H: embryonic day 9.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1tm1.1Zzy (more )
Note: Conditional mutant. Double labeled: gray - Ctnnb1; green and red - Cre reporter.
Structure Level Pattern Image Note
TS15: outflow tract distal part Present Regionally restricted 6H , 6F Organization of cardiac layers disrupted: cardiomyocytes loosely and disorderly arranged, and myocardium multilayered.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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