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Gene Expression Data
Assay Details
Assay
Reference: J:263030 Hu J, et al., WDR1-regulated actin dynamics is required for outflow tract and right ventricle development. Dev Biol. 2018 Jun 15;438(2):124-137
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6715544
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Results
Specimen S3A: embryonic day 9.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: mesenchyme derived from splanchnopleure Present S3A

Specimen S3B: embryonic day 9.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1tm1.1Zzy (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: mesenchyme derived from splanchnopleure Present S3B Percentrage of expressing cells in splanchnic mesoderm unchanged compared with control.

Specimen S4A: embryonic day 9.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1+ (more )
Note: Conditional mutant. Double labeled: gray - Mki67; red - Isl1 (assay MGI:6715547).
Structure Level Pattern Image Note
TS15: outflow tract Present S4A Cell proliferation in outflow tract and right ventricle was similar in control and mutant.
TS15: primitive ventricle Present S4A Cell proliferation in outflow tract and right ventricle was similar in control and mutant.

Specimen S4B: embryonic day 9.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1tm1.1Zzy (more )
Note: Conditional mutant. Double labeled: gray - Mki67; red - Isl1 (assay MGI:6715547).
Structure Level Pattern Image Note
TS15: outflow tract Present S4B Cell proliferation in outflow tract and right ventricle was similar in control and mutant.
TS15: primitive ventricle Present S4B Cell proliferation in outflow tract and right ventricle was similar in control and mutant.

Specimen E10.5 CTL not shown: embryonic day 10.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: outflow tract Present Cell proliferation in outflow tract and right ventricle was similar in control and mutant.
TS17: primitive ventricle Present Cell proliferation in outflow tract and right ventricle was similar in control and mutant.

Specimen E10.5 shfKO not shown: embryonic day 10.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1tm1.1Zzy (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: outflow tract Present Cell proliferation in outflow tract and right ventricle was similar in control and mutant.
TS17: primitive ventricle Present Cell proliferation in outflow tract and right ventricle was similar in control and mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory