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Gene Expression Data
Assay Details
Assay
Reference: J:64996 Burgess RW, et al., Agrin isoforms with distinct amino termini. Differential expression, localization, and function. J Cell Biol. 2000 Oct 2;151(1):41-52
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6714259
Gene symbol: Agrn
Gene name: agrin
Reporter: lacZ
Direct Detection
Results
Specimen 6A: embryonic day 14.0; AgrnGt(Ex192)Byg/Agrn+ (more )
Structure Level Pattern Image Note
TS22: brain blood vessel Present Regionally restricted 6A Expression in small cerebral blood vessels.

Specimen 6B: embryonic day 14.0; AgrnGt(Ex192)Byg/Agrn+ (more )
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Strong Regionally restricted 6B Expression in neural progenitors, highest levels in ventricular zone, of cerebral cortex.
TS22: cerebral cortex intermediate zone Present Regionally restricted 6B Expression in neural progenitors in intermediate zones of cerebral cortex.
TS22: cortical plate Absent 6B

Specimen 6D: embryonic day 18.0; AgrnGt(Ex192)Byg/Agrn+ (more )
Structure Level Pattern Image Note
TS26: hippocampus Present Regionally restricted 6D Expression restricted to near ventricles and in blood vessels.

Specimen 6E: embryonic day 18.0; AgrnGt(Ex192)Byg/Agrn+ (more )
Structure Level Pattern Image Note
TS26: dorsal root ganglion Present Regionally restricted 6E Expression in sensory neurons of dorsal root ganglion.
TS26: spinal cord Strong Regionally restricted 6E Strong expression in motoneurons in spinal cord.

Specimen not shown: embryonic day 18.0; AgrnGt(Ex192)Byg/Agrn+ (more )
Structure Level Pattern Image Note
TS26: trigeminal ganglion Present

Specimen 6G: embryonic day 18.0; AgrnGt(Ex192)Byg/Agrn+ (more )
Structure Level Pattern Image Note
TS26: epidermis Present Regionally restricted 6G Expression in epidermal cells abutting the basal lamina separating dermis from epidermis.

Specimen 6H: embryonic day 18.0; AgrnGt(Ex192)Byg/Agrn+ (more )
Structure Level Pattern Image Note
TS26: brain nucleus Strong Regionally restricted 6H Expression in cranial nerve motor nuclei in hindbrain, including oculomotor nuclei.

Specimen 6I: postnatal adult; AgrnGt(Ex192)Byg/Agrn+ (more )
Structure Level Pattern Image Note
TS28: nervous system Present Regionally restricted 6I Expression in motoneurons persisted into adulthood.

Specimen 6J: embryonic day 18.0; AgrnGt(Ex192)Byg/Agrn+ (more )
Structure Level Pattern Image Note
TS26: glomerular tuft Present 6J Expression in kidney glomeruli and a subset of tubules.
TS26: renal tubule Present 6J Expression in kidney glomeruli and a subset of tubules.

Specimen 6K: embryonic day 18.0; AgrnGt(Ex192)Byg/Agrn+ (more )
Structure Level Pattern Image Note
TS26: lung epithelium Present 6K Expression in pulmonary epithelial cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory