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Gene Expression Data
Assay Details
Assay
Reference: J:243203 Farmer DT, et al., miR-205 is a critical regulator of lacrimal gland development. Dev Biol. 2017 Jul 01;427(1):12-20
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6712433
Gene symbol: Mir205
Gene name: microRNA 205
Reporter: lacZ
Direct Detection
Results
Specimen 3A E12.5 Wholemount: embryonic day 12.5; Mir205tm1.1Mtm/Mir205+ (more )
Structure Level Pattern Image Note
TS20: face skin Present Regionally restricted 3A E12.5 left Expressed in the surface ectoderm neighboring the developing eye.
Specimen 3A E12.5 Section: embryonic day 12.5; Mir205tm1.1Mtm/Mir205+ (more )
Structure Level Pattern Image Note
TS20: face skin Present Regionally restricted 3A E12.5 right Expressed in the surface ectoderm neighboring the developing eye.
Specimen 3A E14.5 Wholemount: embryonic day 14.5; Mir205tm1.1Mtm/Mir205+ (more )
Structure Level Pattern Image Note
TS22: lacrimal gland bud Present 3A E14.5 left
Specimen 3A E14.5 Section: embryonic day 14.5; Mir205tm1.1Mtm/Mir205+ (more )
Structure Level Pattern Image Note
TS22: lacrimal gland bud Present Regionally restricted 3A E14.5 right Expressed in the epithelium.
Specimen 3A E16.5 Wholemount: embryonic day 16.5; Mir205tm1.1Mtm/Mir205+ (more )
Structure Level Pattern Image Note
TS24: lacrimal gland Present 3A E16.5 left
Specimen 3A E16.5 Section: embryonic day 16.5; Mir205tm1.1Mtm/Mir205+ (more )
Structure Level Pattern Image Note
TS24: lacrimal gland epithelium Present 3A E16.5 right
Specimen 3A P0 Wholemount: postnatal day 0; Mir205tm1.1Mtm/Mir205+ (more )
Structure Level Pattern Image Note
TS27: lacrimal gland Present 3A P0 left
Specimen 3A P0 Section: postnatal day 0; Mir205tm1.1Mtm/Mir205+ (more )
Structure Level Pattern Image Note
TS27: lacrimal gland epithelium Present 3A P0 right
Specimen 3A P28 Wholemount: postnatal day 28; Mir205tm1.1Mtm/Mir205+ (more )
Structure Level Pattern Image Note
TS28: lacrimal drainage system Present 3A P28 left
Specimen 3A P28 Section: postnatal day 28; Mir205tm1.1Mtm/Mir205+ (more )
Structure Level Pattern Image Note
TS28: lacrimal drainage system Present Regionally restricted 3A P28 right Expressed in cell populations around the ducts.
TS28: lacrimal gland Present Scattered 3A P28 right Scattered between acinar cells.
Specimen 3B Control: embryonic day 15.5; Mir205tm1.1Mtm/Mir205+ (more )
Structure Level Pattern Image Note
TS23: lacrimal gland bud Present 3B control
Specimen 3B KO: embryonic day 15.5; Mir205tm1.1Mtm/Mir205tm1.1Mtm (more )
Structure Level Pattern Image Note
TS23: lacrimal gland bud Present 3B KO-2 , 3B KO-1 Smaller and poorly extended compared to littermate controls (25% of the homozygous). In greater than 50% of knockout animals, no lacrimal glands were identified.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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