Lefty1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:295945 Kawamura N, et al., Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism. Cell Rep. 2020 Jun 9;31(10):107733
Assay type:	RNA in situ
MGI Accession ID:	MGI:6711980
Gene symbol:	Lefty1
Gene name:	left right determination factor 1

Probe:	Lefty1 probe12
Probe preparation:	Antisense RNA

Results

S1B wt ©

Specimen S1B WT: embryonic day 6.5 (more

)

Structure	Level	Pattern	Image	Note
TS9: embryo	Present	Regionally restricted	S1B wt	Expressed at the anterior side.

S1B -/- I ©

Specimen S1B -/- I: embryonic day 6.5; Rab7^tm1.2Ywd/Rab7^tm1.2Ywd (more

)

Structure	Level	Pattern	Image	Note
TS9: embryo	Present	Regionally restricted	S1B -/- I	Reduced expression at the anterior side in about a half of the mutant embryos.

S1B -/- II ©

Specimen S1B -/- II: embryonic day 6.5; Rab7^tm1.2Ywd/Rab7^tm1.2Ywd (more

)

Structure	Level	Pattern	Image	Note
TS9: embryo	Absent		S1B -/- II	In about a half of the mutant embryos.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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