Axin2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:295945 Kawamura N, et al., Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism. Cell Rep. 2020 Jun 9;31(10):107733
Assay type:	RNA in situ
MGI Accession ID:	MGI:6711852
Gene symbol:	Axin2
Gene name:	axin 2

Probe:	Axin2 probe23
Probe preparation:	Antisense RNA

Results

2D wt ©

Specimen 2D WT: embryonic day 6.5 (more

)

Structure	Level	Pattern	Image	Note
TS9: embryo	Present		2D wt

2D -/- ©

Specimen 2D -/-: embryonic day 6.5; Rab7^tm1.2Ywd/Rab7^tm1.2Ywd (more

)

Structure	Level	Pattern	Image	Note
TS9: embryo	Trace		2D -/-	Almost absent in mutants.

3B-3 ©

Specimen 3B flox/-: embryonic day 7.75; Rab7^tm1.1Ywd/Rab7^tm1.2Ywd (more

)

Structure	Level	Pattern	Image	Note
TS11: embryo	Present		3B-3

3B-4 ©

Specimen 3B cKO: embryonic day 7.75; Rab7^tm1.1Ywd/Rab7^tm1.2Ywd, Tg(Ttr-cre)1Hadj/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS11: embryo	Weak		3B-4	Significantly reduced expression compared with the wild-type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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