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Gene Expression Data
Assay Details
Assay
Reference: J:241850 Naiman N, et al., Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711814
Gene symbol: Podxl
Gene name: podocalyxin-like
Antibody: anti-Podxl (MAB1556)
Detection system: Secondary antibody coupled to DyLight
Results
Specimen 2M: embryonic day 18.5; Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Double labeled: blue - Podxl; green - Lotus tetragonolobus lectin
Structure Level Pattern Image Note
TS26: visceral epithelium of mature renal corpuscle Present 2M Expression is seen in podocytes.
TS26: renal small blood vessel Weak 2M Expression is seen in the endothelium.
Specimen 2N: embryonic day 18.5; Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Double labeled: blue - Podxl; green - Lotus tetragonolobus lectin
Structure Level Pattern Image Note
TS26: visceral epithelium of mature renal corpuscle Absent 2N No podocyte expression is seen.
TS26: renal small blood vessel Weak 2N Expression is seen in the endothelium.
Specimen 2M': embryonic day 18.5; Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: blue - Podxl; red - Umod (assay MGI:6711813); green - Lotus tetragonolobus lectin
Structure Level Pattern Image Note
TS26: visceral epithelium of mature renal corpuscle Present 2M' Expression is seen in podocytes.
TS26: renal small blood vessel Weak 2M' Expression is seen in the endothelium.
Specimen 2N': embryonic day 18.5; Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: blue - Podxl; red - Umod (assay MGI:6711813); green - Lotus tetragonolobus lectin
Structure Level Pattern Image Note
TS26: visceral epithelium of mature renal corpuscle Absent 2N' No podocyte expression is seen.
TS26: renal small blood vessel Weak 2N' Expression is seen in the endothelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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