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Gene Expression Data
Assay Details
Assay
Reference: J:93609 Fuccillo M, et al., Temporal requirement for hedgehog signaling in ventral telencephalic patterning. Development. 2004 Oct;131(20):5031-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6693508
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase3
Detection system: Secondary antibody
Results
Specimen 2C: embryonic day 10.5 (more )
Note: Double labeled: red - Casp3; green - Tubb3 (assay MGI:6693507).
Structure Level Pattern Image Note
TS17: telencephalon Present 2C

Specimen 2D: embryonic day 10.5; Foxg1tm1(cre)Skm/Foxg1+, Smotm1Amc/Smotm2Amc (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Tubb3 (assay MGI:6693507).
Structure Level Pattern Image Note
TS17: telencephalon Present 2D A significant increase in both ventral and dorsal cell death as compared with wild-type controls, with a larger portion of the death occurring in the lateral cortex.

Specimen 2E: embryonic day 12.5 (more )
Note: Double labeled: red - Casp3; green - Tubb3 (assay MGI:6693507).
Structure Level Pattern Image Note
TS20: telencephalon Present 2E

Specimen 2F: embryonic day 12.5; Foxg1tm1(cre)Skm/Foxg1+, Smotm1Amc/Smotm2Amc (more )
Note: Conditional mutant. Double labeled: red - Casp3; green - Tubb3 (assay MGI:6693507).
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 2F Expressed throughout the dorsal-ventral extent, with the exception of the developing hippocampal primordium and choroid plexus (dorsal cortical midline).

Specimen not shown: embryonic day 9.5; Foxg1tm1(cre)Skm/Foxg1+, Smotm1Amc/Smotm2Amc (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: telencephalon Present Increased expression in the cortex more posteriorly.

Specimen not shown: embryonic day 10.5; Foxg1tm1(cre)Skm/Foxg1+, Smotm1Amc/Smotm2Amc (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: telencephalon Present Increased expression in the cortex more posteriorly.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/09/2025
MGI 6.24
The Jackson Laboratory